SCHEMBL11367455

SCHEMBL11367455

C=CCN1C(=O)N(CN2C(=O)N(CC=C)C(C)(C)C2=O)C(=O)C1(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.40
TSHR P16473 1/20 0.40
POLB P06746 3/20 0.38
RAB9A P51151 1/20 0.36
CYP3A4 P08684 1/20 0.34
CNR1 P21554 2/20 0.33
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11221046 0.91 GAA (0.44) GAATSHRPOLBRAB9ACYP3A4
SCHEMBL11367271 0.85 GAA (0.43) GAATSHRPOLBRAB9ACYP3A4
SCHEMBL11373262 0.78 GAA (0.36) GAATSHRPOLBCYP3A4CNR1
SCHEMBL11372133 0.77 RAB9A (0.35) GAATSHRRAB9A
SCHEMBL11368719 0.75 GAA (0.39) GAATSHRPOLBRAB9ACNR1
SCHEMBL11372927 0.75 GAA (0.45) GAATSHRPOLBCNR1MAPT
SCHEMBL4841706 0.73 GAA (0.45) GAATSHRPOLBCYP3A4CNR1
SCHEMBL11794619 0.72 RAB9A (0.43) POLBRAB9A
SCHEMBL1884635 0.72 RAB9A (0.40) POLBRAB9A
SCHEMBL11669066 0.72 GAA (0.36) GAATSHRPOLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4091223-A CROSSLINKERS FOR PVC, POLYETHYLENE, VINYL ACETATE COPOLYMERS CIBA-GEIGY CORPORATION (US) 1978-05-23 US claimed
US-4258149-A AND AN ORGANIC PEROXIDE CATALYST OR RADIATION CIBA-GEIGY CORPORATION (US) 1981-03-24 US disclosed
US-4167465-A Unsaturated hydantoin coagents CIBA-GEIGY CORPORATION (US) 1979-09-11 US disclosed
US-4091223-A CROSSLINKERS FOR PVC, POLYETHYLENE, VINYL ACETATE COPOLYMERS CIBA-GEIGY CORPORATION (US) 1978-05-23 US disclosed