SCHEMBL1884635

SCHEMBL1884635

CC1(C)C(=O)N(CN2C(=O)N(CCO)C(C)(C)C2=O)C(=O)N1CCO

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.40
POLB P06746 1/20 0.39
TAS2R8 Q9NYW2 1/20 0.36
HTR1A P08908 4/20 0.33
HTR7 P34969 4/20 0.33
HTR6 P50406 4/20 0.33
PLA2G7 Q13093 2/20 0.33
PGR P06401 1/20 0.32
AR P10275 1/20 0.32
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476583 0.90 RAB9A (0.38) RAB9APOLBTAS2R8HTR1AHTR7
SCHEMBL11710779 0.87 HTR1A (0.38) RAB9ATAS2R8HTR1AHTR7HTR6
SCHEMBL13853139 0.85 RAB9A (0.41) RAB9ATAS2R8HTR1AHTR7HTR6
SCHEMBL11708627 0.85 HTR1A (0.40) RAB9ATAS2R8HTR1AHTR7HTR6
SCHEMBL11052545 0.85 RAB9A (0.47) RAB9APOLBTAS2R8HTR1AHTR7
Ethylenediamine SCHEMBL10954391 0.84 PLA2G7 (0.37) RAB9ATAS2R8HTR1AHTR7HTR6
SCHEMBL11637356 0.82 RAB9A (0.52) RAB9ATAS2R8MMP2MMP3KMT2A
SCHEMBL1885135 0.80 POLB (0.32) RAB9APOLB
SCHEMBL13853150 0.80 RAB9A (0.40) RAB9ATAS2R8HTR1AHTR7HTR6
SCHEMBL11426999 0.80 PTGS1 (0.42) RAB9ATAS2R8HTR1AHTR7HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100297374-A1 In Situ Moisture Generation and Use of Polyfunctional Alcohols for Crosslinking of Silane-Functionalized Resins DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-25 US claimed
WO-2018219574-A1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS HENKEL AG & CO. KGAA (DE) 2018-12-06 WO disclosed
EP-3409707-A1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS Henkel AG & Co. KGaA (DE) 2018-12-05 EP disclosed
EP-2207851-B1 IN SITU MOISTURE GENERATION AND USE OF POLYFUNCTIONAL ALCOHOLS FOR CROSSLINKING OF SILANE-FUNCTIONALIZED RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-25 EP disclosed
EP-1891142-B1 OLIGO- AND POLY-CARBONATES TERMINATED WITH SILICON CONTAINING GROUPS AS SURFACE MODIFIERS CIBA HOLDING INC (CH) 2014-12-03 EP disclosed
US-8460770-B2 In situ moisture generation and use of polyfunctional alcohols for crosslinking of silane-functionalized resins DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-11 US disclosed
US-8013047-B2 Oligo- and poly-carbonates terminated with silicon containing groups as surface modifiers BASF SE Ludwigshafen (DE) 2011-09-06 US disclosed
US-7947767-B2 Electret materials BASF SE (DE) 2011-05-24 US disclosed
US-20100297374-A1 In Situ Moisture Generation and Use of Polyfunctional Alcohols for Crosslinking of Silane-Functionalized Resins DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-25 US disclosed
US-7790807-B2 polycarbonate endcapped with perfluoroalkanol (Zonyl\") incorporated into a polyester, polyacrylate, polymethacrylate or polypropylene via extrusion; self cleaning; antisoiling, oil resistance, solvent resistance, chemical resistance, scratch resistance, hydrophobic; molding material CIBA SPECIALTY CHEMICALS CORP. (US) 2010-09-07 US disclosed
US-4499219-A CONTAINING AN EXPXIDE AND BISOXAZOLINE, DIIMIDE OR TRIACYLAMINE;HEAT RESISTANCE CIBA-GEIGY CORPORATION (US) 1985-02-12 US disclosed
US-4456723-A POLYESTER WITH ANHYDROUS CALCIUM PHOSPHATE CIBA-GEIGY CORPORATION (US) 1984-06-26 US disclosed
US-4401784-A ADDING DOLOMITE TO INCREASE STIFFNESS AND DIMENSIONAL STABILITY UNDER HEAT CIBA-GEIGY CORPORATION (US) 1983-08-30 US disclosed
US-4281103-A Dicarboxylic acids containing triazine rings, and polyesters formed from these dicarboxylic acids CIBA-GEIGY CORPORATION (US) 1981-07-28 US disclosed
US-4228281-A PRODUCE THERMOPLASTIC POLYESTERS HAVING HIGH GLASS TRANSITION TEMPERATURES AND HIGH DIMENSIONAL STABILITY UNDER HEAT CIBA-GEIGY CORPORATION (US) 1980-10-14 US disclosed
US-4163099-A DICARBOXYLIC ACID CONTAINING AMIDE SUBSTITUTED ARENE RING OR AMINO SUBSTITUTED S-TRIAZINE RING; MOLDING MATERIAL CIBA-GEIGY CORPORATION (US) 1979-07-31 US disclosed
US-4148956-A TOUGH POLYESTERS WITH ACRYLONITRILE-STYRENE, MODIFIED WITH ACRYLATE, COPOLYMER ALKOR GMBH (DE) 1979-04-10 US disclosed
US-4139512-A THERMOPLASTIC CIBA-GEIGY CORPORATION (US) 1979-02-13 US disclosed
US-4108834-A N,N-HETEROCYCLIC DIOLS CIBA-GEIGY CORPORATION (US) 1978-08-22 US disclosed
US-4104297-A Thermoplastic polyesters prepared from dicarboxylic acids containing N-heterocyclic rings CIBA-GEIGY CORPORATION (US) 1978-08-01 US disclosed