Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358618 | 0.98 | POLB (0.53) | POLBMAPTMAPK1HSD17B10GSK3A | |
| SCHEMBL11367742 | 0.95 | POLB (0.53) | POLBMAPTMAPK1HSD17B10GSK3A | |
| SCHEMBL11367971 | 0.89 | POLB (0.45) | POLBMAPTMAPK1HSD17B10GSK3A | |
| SCHEMBL11377070 | 0.89 | POLB (0.45) | POLBMAPTMAPK1HSD17B10GSK3A | |
| SCHEMBL11367667 | 0.87 | POLB (0.46) | POLBMAPTMAPK1HSD17B10GSK3A | |
| SCHEMBL11372018 | 0.84 | POLB (0.46) | POLBMAPTMAPK1HSD17B10GSK3A | |
| SCHEMBL9389184 | 0.81 | GSK3A (0.61) | POLBMAPTGSK3AGSK3BALDH1A1 | |
| SCHEMBL11366882 | 0.80 | ALDH1A1 (0.49) | POLBMAPTMAPK1HSD17B10GSK3A | |
| SCHEMBL11376362 | 0.80 | LMNA (0.57) | MAPTMAPK1HSD17B10ALDH1A1LMNA | |
| SCHEMBL11377863 | 0.78 | ALDH1A1 (0.58) | POLBMAPTMAPK1HSD17B10GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |