Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369119 | 0.90 | ADRB3 (0.44) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL11365731 | 0.87 | ADRB2 (0.48) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL11366337 | 0.86 | ADRB2 (0.47) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL11571740 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BADRB2ADRB1DRD2 | |
| SCHEMBL11367767 | 0.83 | ADRB2 (0.44) | MTNR1AMTNR1BADRB2ADRB1DRD2 | |
| SCHEMBL11373565 | 0.82 | ADRB2 (0.46) | ADRB2ADRB1DRD2DRD4DRD3 | |
| SCHEMBL11374980 | 0.82 | ADRB2 (0.45) | ADRB2ADRB1DRD1ADRB3SLC6A2 | |
| SCHEMBL11367805 | 0.81 | ADRB2 (0.44) | ADRB2ADRB1DRD2DRD1DRD3 | |
| SCHEMBL11371511 | 0.73 | ADRB3 (0.43) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL11574999 | 0.73 | ADRB3 (0.48) | ADRB2ADRB1DRD3ADRB3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304790-A | 2-(Alkylthio, alkylsulfinyl or alkylsulfonyl)-4-[2-anilinoalkylamino)-1-hydroxyethyl]phenols and derivatives thereof | SCHERING CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |