Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PRKCH | P24723 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370533 | 0.89 | SYK (0.58) | SYKKDM4EGLANPSR1RXFP1 | |
| SCHEMBL11373416 | 0.85 | KDM4E (0.58) | SYKKDM4EGLANPSR1RXFP1 | |
| SCHEMBL11374306 | 0.83 | PRKCD (0.56) | CYP1A2PRKCHPRKCEPRKCQPRKCD | |
| SCHEMBL31375795 | 0.83 | PRKCD (0.56) | CYP1A2PRKCHPRKCEPRKCQPRKCD | |
| SCHEMBL11366860 | 0.81 | PRKCD (0.45) | KDM4ECYP1A2RAB9APRKCHPRKCE | |
| SCHEMBL11375277 | 0.80 | KDM4E (0.50) | KDM4EGLACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL508360 | 0.78 | SYK (0.56) | SYKKDM4EDYRK1ANPC1RAB9A | |
| SCHEMBL11366250 | 0.78 | CYP1A2 (0.51) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11365506 | 0.77 | LATS1 (0.47) | CYP1A2PRKCHPRKCEPRKCQPRKCD | |
| SCHEMBL11365490 | 0.77 | ALDH1A1 (0.47) | NPSR1DYRK1ACYP2D6CYP2C9CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260759-A | CONDENSATION OF NITRILES | SCHERING-CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4115395-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4107166-A | ANTIFUNGAL, ANTIBACTERIAL | SCHERING CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |
| US-4017500-A | FUNGICIDES, BACTERICIDES | SCHERING CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |