Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368203 | 1.00 | ALDH1A1 (0.45) | ALDH1A1POLBIKBKBGAAPIM1 | |
| SCHEMBL7454578 | 0.83 | MAPT (0.44) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7454571 | 0.83 | MAPT (0.44) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9672531 | 0.78 | POLB (0.55) | ALDH1A1POLBGAAPTGS2RAB9A | |
| SCHEMBL9672527 | 0.78 | POLB (0.55) | ALDH1A1POLBGAAPTGS2RAB9A | |
| SCHEMBL11368426 | 0.75 | LMNA (0.46) | ALDH1A1POLBIKBKBGAANPC1 | |
| SCHEMBL11368424 | 0.75 | LMNA (0.46) | ALDH1A1POLBIKBKBGAANPC1 | |
| SCHEMBL21439832 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1POLBGAANPC1RAB9A | |
| SCHEMBL21439833 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1POLBGAANPC1RAB9A | |
| SCHEMBL10493472 | 0.74 | MAPT (0.41) | ALDH1A1POLBGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251524-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-17 | — | — | US | disclosed |
| US-4200576-A | CEPHALOSPORINS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-04-29 | — | — | US | disclosed |
| US-4147693-A | βLactam antibiotics and process for their use | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |