Acetic Acid

Acetic Acid

SCHEMBL11368283

CC(=O)[O-].CC(C)[N+](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.53

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.53
CA4 P22748 2/20 0.39
BBOX1 O75936 2/20 0.36
CA2 P00918 1/20 0.35
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL11380330 0.79 CA2 (0.42) CA1BBOX1CA2TSHR
Acetic Acid SCHEMBL241961 0.78
Acetic Acid SCHEMBL1026309 0.78 CA1 (0.89) CA1CA4CA2ALDH1A1TDP1
Acetic Acid SCHEMBL319665 0.78 CA1 (0.50) CA1CA4BBOX1CA2ALDH1A1
Acetic Acid SCHEMBL11574110 0.74
Acetic Acid SCHEMBL2944150 0.73 CA1 (0.80) CA1CA4CA2ALDH1A1TDP1
Acetic Acid SCHEMBL15618797 0.73 CA1 (0.80) CA1CA4CA2ALDH1A1TDP1
Acetic Acid SCHEMBL94541 0.73 CA1 (0.80) CA1CA4CA2ALDH1A1TDP1
Acetic Acid SCHEMBL28041826 0.73 CA1 (0.80) CA1CA4CA2ALDH1A1TDP1
Acetic Acid SCHEMBL28776496 0.73 CA1 (0.80) CA1CA4CA2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3548575-A1 ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES Momentive Performance Materials Inc. (US) 2019-10-09 EP claimed
WO-2018102510-A1 ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-06-07 WO claimed
US-20180148601-A1 ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES MOMENTIVE PERFORMANCE MATERIALS INC. 2018-05-31 US claimed
EP-3768763-B1 SILICONE POLYMER AND COMPOSITION COMPRISING THE SAME MOMENTIVE PERFORMANCE MAT INC (US) 2026-04-29 EP disclosed
EP-4665777-A1 HYDROPHILIC COPOLYMER AND COATING COMPOSITION COMPRISING THE SAME AND ANTIFOG USE THEREOF Momentive Performance Materials Inc. (US) 2025-12-24 EP disclosed
EP-3935114-B1 PROTECTIVE COATING COMPOSITION AND COATED METALLIC SUBSTRATE COMPRISING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2025-07-16 EP disclosed
EP-3768762-B1 SILICONE POLYMER MOMENTIVE PERFORMANCE MAT INC (US) 2025-02-19 EP disclosed
WO-2024168819-A1 HYDROPHILIC COPOLYMER AND COATING COMPOSITION COMPRISING THE SAME AND ANTIFOG USE THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2024-08-22 WO disclosed
CN-118515810-A Hydrophilic copolymers and coating compositions containing them and their anti-fog uses 迈图高新材料公司 2024-08-20 CN disclosed
US-11939490-B2 Curable surface-protective coating composition, processes for its preparation and application to a metallic substrate and resulting coated metallic substrate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2024-03-26 US disclosed
CN-113692432-B Protective coating composition and coated metal substrate comprising the same 迈图高新材料公司 2023-10-20 CN disclosed
WO-2019182857-A1 SILICONE POLYMER MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-09-26 WO disclosed
WO-2019182854-A1 A THERMAL CONDUCTING SILICONE POLYMER COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-09-26 WO disclosed
WO-2019027991-A1 CURABLE SURFACE-PROTECTIVE COATING COMPOSITION, PROCESSES FOR ITS PREPARATION AND APPLICATION TO A METALLIC SUBSTRATE AND RESULTING COATED METALLIC SUBSTRATE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-02-07 WO disclosed
US-20190031918-A1 CURABLE SURFACE-PROTECTIVE COATING COMPOSITION, PROCESSES FOR ITS PREPARATION AND APPLICATION TO A METALLIC SUBSTRATE AND RESULTING COATED METALLIC SUBSTRATE MOMENTIVE PERFORMANCE MATERIALS INC. 2019-01-31 US disclosed
WO-2018102510-A1 ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-06-07 WO disclosed
US-20180148601-A1 ABRASION RESISTANT COATING COMPOSITION WITH INORGANIC METAL OXIDES MOMENTIVE PERFORMANCE MATERIALS INC. 2018-05-31 US disclosed
US-4255553-A COMPRISING A COMPOUND HAVING AT LEAST TWO EPOXY GROUPS, A POLYESTER OR ACRYLIC RESIN, AND A QUARTERNARY AMMONIUM CARBOXYLATE AS CATALYST TOYO BOSEKI KABUSHIKI KAISHA (JP) 1981-03-10 US disclosed
US-4254282-A Process for preparing cis-3-(2,2-dihalovinyl)-2,2-dimethylcyclopropanecarboxylic acid FMC CORPORATION (US) 1981-03-03 US disclosed
EP-0003666-A1 Oxabicyclo 3.1.0 hexanes useful in the production of cyclopropanecarboxylate insecticides and intermediate compounds FMC Corporation (US) 1979-08-22 EP disclosed