Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28807804 | 0.84 | CA1 (0.59) | GAAMAPTCA1CA2MEN1 | |
| SCHEMBL23121534 | 0.82 | GAA (0.44) | GAAMAPTMPOSIGMAR1CA1 | |
| SCHEMBL6142706 | 0.80 | CHRM2 (0.60) | GAAMAPTMPOSIGMAR1BCHE | |
| Sulfuric Acid SCHEMBL28807803 | 0.78 | CA2 (0.68) | GAAMAPTKDM4EALDH1A1CA1 | |
| SCHEMBL11359616 | 0.75 | CHRM2 (0.44) | MAPTKDM4EALDH1A1CA1CA2 | |
| SCHEMBL10742212 | 0.75 | CYP1A2 (0.49) | GAAMAPTMPOSIGMAR1ALDH1A1 | |
| SCHEMBL16296096 | 0.74 | CA1 (0.64) | GAAMAPTSIGMAR1CA1CA2 | |
| SCHEMBL27228 | 0.73 | GAA (0.95) | GAAMAPTMPOSIGMAR1KDM4E | |
| SCHEMBL21049878 | 0.72 | GAA (0.63) | GAAMAPTMPOSIGMAR1KDM4E | |
| SCHEMBL29802812 | 0.72 | CA12 (0.64) | GAAMAPTMPOSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279819-A | GASTROINTESTINAL DISORDERS | ALLEN & HANBURYS LTD. (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4255440-A | ANTIALLERGENS, ANTIULCER AGENTS | ALLEN & HANBURYS LIMITED (GB) | 1981-03-10 | — | — | US | disclosed |
| US-4169855-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | Allen & Hansbury, Limited (GB) | 1979-10-02 | — | — | US | disclosed |
| US-4128658-A | HISTAMINE ANTAGONISTS | ALLEN & HANBURYS LIMITED (GB) | 1978-12-05 | — | — | US | disclosed |