Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505320 | 0.81 | CYP4A11 (0.60) | ALDH1A1MAPTTHRBTHRAHRH1 | |
| SCHEMBL11305151 | 0.79 | CA12 (0.47) | ALDH1A1MAPTTHRBTHRAKCNH2 | |
| SCHEMBL2292715 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL7020219 | 0.79 | ESR1 (0.48) | ALDH1A1KMT2ATBXAS1KDM4EGAA | |
| SCHEMBL371605 | 0.78 | RARB (0.71) | RARBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL133470 | 0.78 | RARB (0.68) | RARBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL18259963 | 0.78 | MEN1 (0.58) | RARBALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL826498 | 0.77 | SLC7A5 (0.51) | ALDH1A1KMT2AMEN1MAPTKCNH2 | |
| SCHEMBL17979185 | 0.76 | MEN1 (0.60) | RARBALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14166065 | 0.76 | ACE2 (0.38) | RARBALDH1A1KMT2AMEN1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260771-A | VASODILATORS, ANTICOAGULANTS, IMMUNOLOGY | MERCK & CO., INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4225609-A | Interphenylene 9-thia-11-oxo-12-aza-prostanoic acids | MERCK & CO., INC. (US) | 1980-09-30 | — | — | US | disclosed |