SCHEMBL133470

SCHEMBL133470

O=C(O)c1ccc(CCCc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.68
ALDH1A1 P00352 2/20 0.63
KMT2A Q03164 2/20 0.63
MEN1 O00255 1/20 0.63
RARA P10276 1/20 0.63
MAPT P10636 1/20 0.63
MTOR P42345 1/20 0.63
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
HDAC8 Q9BY41 1/20 0.57
PTGER1 P34995 1/20 0.56
PTGER4 P35408 1/20 0.56
PTGER3 P43115 1/20 0.56
PTGER2 P43116 1/20 0.56
TBXAS1 P24557 2/20 0.54
HSD17B10 Q99714 1/20 0.53
SRD5A2 P31213 1/20 0.52
HDAC1 Q13547 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL371605 0.95 RARB (0.71) RARBALDH1A1KMT2AMEN1RARA
SCHEMBL1982703 0.93 HDAC8 (0.67) RARBALDH1A1KMT2AMEN1RARA
SCHEMBL15583704 0.93 RARB (0.72) RARBALDH1A1KMT2AMEN1RARA
SCHEMBL9472454 0.93 RARB (0.72) RARBALDH1A1KMT2AMEN1RARA
SCHEMBL30053056 0.93 RARB (0.72) RARBALDH1A1KMT2AMEN1RARA
SCHEMBL28873230 0.93 RARB (0.72) RARBALDH1A1KMT2AMEN1RARA
SCHEMBL19301332 0.91 RARB (0.59) RARBALDH1A1KMT2AMEN1RARA
SCHEMBL9101705 0.91 CA12 (0.67) RARBALDH1A1KMT2AMEN1RARA
SCHEMBL70166 0.90 TSHR (0.67) RARBALDH1A1KMT2AMEN1RARA
Terephthalic Acid SCHEMBL4612225 0.90 TSHR (0.67) RARBALDH1A1KMT2AMEN1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3559081-B1 GLYCOLIC ACID POLYMER SOLVAY (BE) 2023-11-22 EP claimed
EP-2555053-B1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES (JP) 2017-10-18 EP claimed
EP-2555053-A1 Positive-type photosensitive resin composition Toray Industries, Inc. (JP) 2013-02-06 EP claimed
CN-117384078-A Novel polymer, diamine compound, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-12 CN disclosed
CN-117384077-A Novel polymer, diamine compound, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-12 CN disclosed
CN-117384076-A Novel polymer, diamine compound, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-12 CN disclosed
US-11802181-B2 Di-amine compound, and heat-resistant resin and resin composition using the same TORAY INDUSTRIES, INC. (JP) 2023-10-31 US disclosed
EP-3363843-B1 RESIN AND PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES (JP) 2023-04-12 EP disclosed
CN-111263761-B Novel polymer and diamine compound 日产化学株式会社 2022-11-04 CN disclosed
US-11347146-B2 Resin composition TORAY INDUSTRIES, INC. (JP) 2022-05-31 US disclosed
US-11333976-B2 Resin, photosensitive resin composition, electronic component and display device using the same TORAY INDUSTRIES, INC. (JP) 2022-05-17 US disclosed
WO-2006006054-A1 METHOD FOR PREPARING A POLYMERIC BIOCOMPATIBLE SYSTEM FOR THE PHARMACOLOGICAL RELEASE BY TOPIC USE AND USE OF SAID SYSTEM UNIVERSITA' DEGLI STUDI DI ROMA 'TOR VERGATA' (IT) 2006-01-19 WO disclosed
US-20050014876-A1 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2005-01-20 US disclosed
EP-1496395-A2 Photosensitive resin precursor composition TORAY INDUSTRIES, INC. (JP) 2005-01-12 EP disclosed
US-20040266916-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-30 US disclosed
EP-1486536-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-12-15 EP disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1452567-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-09-01 EP disclosed
US-6753363-B1 BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY POLYPLASTICS CO., LTD. (JP) 2004-06-22 US disclosed
US-4990567-A Polyamide, modified polyolefin blend; reaction injection molding MITSUBISHI KASEI POLYTEC COMPANY (JP) 1991-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11802181-B2 Di-amine compound, and heat-resistant resin and resin composition using the same CAD, ARID2, SMC3 RARB 1384/4885ALDH1A1 2539/4885KMT2A 1021/4885
US-11333976-B2 Resin, photosensitive resin composition, electronic component and display device using the same EED, RPL19, RARA RARB 22/4885ALDH1A1 1480/4885KMT2A 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.