Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 3/20 | 0.46 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340234 | 0.91 | GCGR (0.59) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL11373906 | 0.89 | NPC1 (0.43) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL11334800 | 0.89 | PNLIP (0.49) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8662642 | 0.88 | PYGL (0.52) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL11324422 | 0.86 | GCGR (0.51) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8657040 | 0.84 | PYGL (0.61) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL11322089 | 0.83 | GCGR (0.51) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL11334947 | 0.81 | PYGL (0.51) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL11251747 | 0.81 | GCGR (0.55) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL11335026 | 0.80 | PYGL (0.42) | NPC1RAB9APOLBPKMPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276309-A | DIPTERA, COLEOPTERA, LEPIDOPTERA | SCHERING AG (DE) | 1981-06-30 | — | — | US | claimed |