Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370596 | 0.86 | KDM4E (0.67) | KMT2AMEN1MAPTUSP2KDM4E | |
| SCHEMBL11377484 | 0.86 | USP2 (0.77) | KMT2AMEN1MAPTUSP2ALDH1A1 | |
| SCHEMBL11362587 | 0.85 | MAPT (0.60) | KMT2AMEN1MAPTUSP2KDM4E | |
| SCHEMBL12259241 | 0.84 | KMT2A (0.96) | KMT2AMEN1MAPTUSP2ALDH1A1 | |
| SCHEMBL11370338 | 0.84 | KCNH2 (0.68) | KMT2AMAPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL11378959 | 0.84 | L3MBTL1 (0.74) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31510206 | 0.84 | MAPT (0.70) | KMT2AMEN1MAPTUSP2ALDH1A1 | |
| SCHEMBL11365440 | 0.81 | TSHR (0.70) | KMT2AMEN1MAPTUSP2ALDH1A1 | |
| SCHEMBL11366315 | 0.80 | L3MBTL1 (0.79) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11371054 | 0.80 | MAPT (0.54) | KMT2AMEN1MAPTUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269838-A | ADRENERGIC BLOCKING AGENTS; ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS | NIPPON SHINYAKU CO. LTD. (JP) | 1981-05-26 | — | — | US | claimed |