Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.52 |
| ▸ | CDK2 | P24941 | 11/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 4/20 | 0.45 |
| ▸ | CCND1 | P24385 | 4/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | CCND2 | P30279 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27174843 | 0.73 | CA1 (0.58) | GRM4CCNE1CDK2CCNE2HSD17B10 | |
| SCHEMBL10009293 | 0.73 | GRM4 (0.65) | GRM4CCNE1CDK2CCNE2CDK5 | |
| SCHEMBL22867203 | 0.71 | GRM4 (0.54) | GRM4CCNE1CDK2CCNE2LMNA | |
| SCHEMBL9045524 | 0.71 | CCNE1 (0.37) | GRM4CCNE1CDK2CCNE2LMNA | |
| SCHEMBL958320 | 0.71 | FBP1 (0.64) | GRM4CCNE1CDK2CCNE2 | |
| SCHEMBL31482769 | 0.70 | GRM4 (0.47) | GRM4CCNE1CDK2CCNE2LMNA | |
| SCHEMBL956877 | 0.70 | GRM4 (0.49) | GRM4CDK2HSD17B10CA1CA12 | |
| SCHEMBL27174928 | 0.70 | GRM4 (0.49) | GRM4CCNE1CDK2CCNE2LMNA | |
| SCHEMBL27174952 | 0.70 | GRM4 (0.52) | GRM4CCNE1CDK2CCNE2LMNA | |
| SCHEMBL27174839 | 0.70 | GRM4 (0.46) | GRM4CCNE1CDK2CCNE2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254260-A | 3-Substituted-7-substituted alkanamido-3-cephem-4-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |