Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376360 | 0.87 | KDM4E (0.51) | NPC1RAB9ALMNAKDM4EPOLB | |
| SCHEMBL76414 | 0.87 | NPC1 (0.61) | NPC1RAB9ALMNATTRKDM4E | |
| SCHEMBL30240912 | 0.87 | NPC1 (0.61) | NPC1RAB9ALMNATTRKDM4E | |
| SCHEMBL11386356 | 0.85 | NPC1 (0.47) | NPC1RAB9ALMNAKDM4EPOLB | |
| SCHEMBL8370972 | 0.83 | TAAR1 (0.50) | NPC1RAB9ALMNAKDM4EPOLB | |
| SCHEMBL11876747 | 0.80 | NPC1 (0.47) | NPC1RAB9ALMNAHPGDALOX15 | |
| SCHEMBL45835 | 0.79 | NPC1 (0.54) | NPC1RAB9ALMNAKDM4EPOLB | |
| SCHEMBL690587 | 0.78 | PPARA (0.48) | — | |
| SCHEMBL29870437 | 0.78 | PPARA (0.48) | — | |
| SCHEMBL9869855 | 0.78 | PPARA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271307-A | Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4076687-A | Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1978-02-28 | — | — | US | disclosed |