SCHEMBL8370972

SCHEMBL8370972

NCCc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.50
MAPK1 P28482 4/20 0.50
KDM4E B2RXH2 4/20 0.50
DRD2 P14416 3/20 0.50
DRD1 P21728 3/20 0.50
ADRA2A P08913 3/20 0.50
SLC6A2 P23975 3/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPT P10636 2/20 0.50
DRD4 P21917 2/20 0.50
DRD5 P21918 2/20 0.50
DRD3 P35462 2/20 0.50
RECQL P46063 2/20 0.50
SLC6A3 Q01959 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
APEX1 P27695 2/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
HTR1A P08908 2/20 0.50
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11386356 0.88 NPC1 (0.47) TAAR1MAPK1KDM4EDRD2DRD1
SCHEMBL11376360 0.86 KDM4E (0.51) MAPK1KDM4EALDH1A1MAPTTDP1
SCHEMBL11368692 0.83 NPC1 (0.49) MAPK1KDM4EALDH1A1MAPTALOX15
SCHEMBL11876747 0.82 NPC1 (0.47) MAPK1MAPTTDP1ALOX15LMNA
SCHEMBL29870437 0.80 PPARA (0.48)
SCHEMBL690587 0.80 PPARA (0.48)
SCHEMBL9869855 0.80 PPARA (0.48)
SCHEMBL3937549 0.79 NPC1 (0.51) KDM4EALDH1A1MAPTTDP1ALOX15
SCHEMBL30058950 0.79 NPC1 (0.51) KDM4EALDH1A1MAPTTDP1ALOX15
SCHEMBL45835 0.75 NPC1 (0.54) KDM4EALDH1A1MAPTTDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0740198-B1 Benzotriazole based UV absorbers and photographic elements containing them EASTMAN KODAK CO (US) 1999-01-20 EP disclosed
EP-0740198-A2 Benzotriazole based UV absorbers and photographic elements containing them EASTMAN KODAK COMPANY (US) 1996-10-30 EP disclosed
US-5500332-A STORAGE STABILITY EASTMAN KODAK COMPANY (US) 1996-03-19 US disclosed