Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15147253 | 0.80 | CHRNA1 (0.45) | GRIN2BOPRL1OPRM1OPRK1CHRNB2 | |
| SCHEMBL34468465 | 0.79 | OPRL1 (0.50) | GRIN2BOPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL11467643 | 0.78 | OPRL1 (0.47) | GRIN2BOPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL21523784 | 0.75 | CYP2D6 (0.41) | GRIN2BOPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL10506035 | 0.75 | OPRM1 (0.48) | GRIN2BOPRL1OPRM1OPRK1CHRNB2 | |
| SCHEMBL11360698 | 0.75 | MAOA (0.39) | MEN1KMT2AMAOA | |
| SCHEMBL4555715 | 0.73 | GRIN2B (0.45) | GRIN2BOPRL1OPRM1OPRK1SLC6A2 | |
| SCHEMBL1668502 | 0.73 | OPRM1 (0.48) | OPRL1OPRM1OPRK1CHRNB2SLC6A2 | |
| SCHEMBL27557278 | 0.73 | OPRL1 (0.45) | GRIN2BOPRL1OPRM1OPRK1CHRNB2 | |
| Hydrochloric Acid SCHEMBL4555247 | 0.72 | SMN1; SMN2 (0.45) | GRIN2BOPRL1OPRM1OPRK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4286014-A | CHAIN EXTENDER COMPRISING HYDRAZINE OR DERIVATIVE | TORAY INDUSTRIES, INCORPORATED (JP) | 1981-08-25 | — | — | US | disclosed |