Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369725 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAPOLBNPC1RAB9A | |
| SCHEMBL11367036 | 0.82 | KDM4E (0.40) | SMN1; SMN2LMNAPOLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11250255 | 0.80 | KDM4E (0.39) | LMNAPOLBNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11250253 | 0.80 | KDM4E (0.39) | LMNAPOLBNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11261314 | 0.79 | KDM4E (0.42) | SMN1; SMN2LMNAPOLBNPC1RAB9A | |
| SCHEMBL11101674 | 0.79 | P2RX3 (0.41) | SMN1; SMN2LMNAPOLBNPC1RAB9A | |
| SCHEMBL11090997 | 0.78 | KDM4E (0.47) | LMNAPOLBNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11089322 | 0.77 | KDM4E (0.46) | LMNAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL11295979 | 0.74 | KDM4E (0.47) | LMNAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL11113730 | 0.74 | KDM4E (0.43) | LMNAPOLBNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252807-A | Fused pyrimidine derivatives and antiatherosclerotic methods of treatment with them | CHINCIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1981-02-24 | — | — | US | claimed |