Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742276 | 0.89 | LMNA (0.44) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL11742209 | 0.86 | CYP1A2 (0.56) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL9687256 | 0.83 | LMNA (0.51) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL21550 | 0.83 | LMNA (0.59) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL8172398 | 0.81 | LMNA (0.57) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL11741962 | 0.81 | LMNA (0.57) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL11740713 | 0.81 | LMNA (0.57) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL11738292 | 0.81 | LMNA (0.57) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL3020961 | 0.81 | LMNA (0.56) | CYP1A2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL7584622 | 0.80 | CYP1A2 (0.58) | CYP1A2LMNAKMT2AMEN1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279908-A | Pyridazine derivatives and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1981-07-21 | — | — | US | disclosed |
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |