Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550 | 0.98 | LMNA (0.59) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11741962 | 0.97 | LMNA (0.57) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11740713 | 0.97 | LMNA (0.57) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11738292 | 0.97 | LMNA (0.57) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11739470 | 0.88 | LMNA (0.49) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11715778 | 0.88 | LMNA (0.51) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11742209 | 0.84 | CYP1A2 (0.56) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11736972 | 0.82 | LMNA (0.60) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11740668 | 0.82 | LMNA (0.51) | LMNAKMT2AMEN1CYP1A2PDE4A | |
| SCHEMBL11369784 | 0.81 | CYP1A2 (0.53) | LMNAKMT2AMEN1CYP1A2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003719-A2 | MICROBICIDAL N-SULFONYLGLYCIN ALKYNYLOXYPHENEMETHYL AMIDE DERIVATIVES | Novartis AG (CH) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007674-A2 | MICROBICIDAL N-SULFONYLGLYCIN ALKYNYLOXYPHENEMETHYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 1999-02-18 | — | — | WO | disclosed |