Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 2/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 3/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 2/20 | 0.35 |
| ▸ | KDM5C | P41229 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857476 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL27945025 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL517935 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL7067358 | 0.78 | CA12 (0.50) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL23830172 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL5249643 | 0.78 | NAPRT (0.46) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL28589292 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL23971140 | 0.78 | SMN1; SMN2 (0.46) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL30411449 | 0.78 | SMN1; SMN2 (0.46) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 | |
| SCHEMBL10762405 | 0.75 | DPP4 (0.52) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267953-A | Tetrahydroimidazo [4,5-C ] pyridine derivatives as inducers of PD-L1 internalization | 因赛特公司 | 2019-09-20 | — | — | CN | disclosed |
| EP-1737451-B1 | MONOCYCLIC HETEROCYCLES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-23 | — | — | EP | disclosed |
| CN-1178939-C | Non-nucleoside reverse transcriptase inhibitors | ���ָ����Ӣ��ķ���ô�����˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1436189-A | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-08-13 | — | — | CN | disclosed |
| EP-0225172-A1 | Process for the preparation of 5-chloro and 5-bromo-2-hydroxynicotinicacids | A.H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-10 | — | — | EP | disclosed |