Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.41 |
| ▸ | GABRE | P78334 | 3/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857454 | 0.82 | NAPRT (0.57) | NAPRTKDM4EALDH1A1GABRPGABRD | |
| SCHEMBL22688908 | 0.79 | NAPRT (0.48) | NAPRTKDM4EALDH1A1GABRPGABRD | |
| SCHEMBL27945025 | 0.79 | KDM4E (0.44) | NAPRTKDM4EALDH1A1GABRPGABRD | |
| SCHEMBL5355271 | 0.78 | NAPRT (0.47) | NAPRTKDM4EALDH1A1GABRPGABRD | |
| SCHEMBL517935 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL1137039 | 0.78 | KDM4E (0.42) | NAPRTKDM4EALDH1A1GABRPGABRD | |
| SCHEMBL20520335 | 0.77 | NAPRT (0.47) | NAPRTKDM4EALDH1A1GABRPGABRD | |
| SCHEMBL23971140 | 0.76 | SMN1; SMN2 (0.46) | NAPRTKDM4EALDH1A1SMN1; SMN2ASPH | |
| SCHEMBL11819966 | 0.76 | NAPRT (0.46) | NAPRTKDM4EALDH1A1GABRPGABRD | |
| SCHEMBL23830172 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2ASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565684-A | 6-pyrromonazole substituted quinazoline compound, and derivative, synthetic method and application thereof | 南方医科大学 | 2017-04-19 | — | — | CN | claimed |
| CN-104592217-B | 3 (1,3,4 oxadiazolyl) 5 phenoxypyridines analog derivative and preparation method and application | 沈阳药科大学 | 2018-03-13 | — | — | CN | disclosed |
| CN-104592217-A | 3-(1, 3, 4-oxadiazol)-5-phenoxy-pyridine derivative, preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-05-06 | — | — | CN | disclosed |
| EP-1781654-A1 | PYRROLO-PYRIDINE KINASE MODULATORS | SGX Pharmaceuticals, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006015123-A1 | PYRROLO-PYRIDINE KINASE MODULATORS | SGX PHARMACEUTICALS, INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| EP-1623216-A2 | COMPOUND LIBRARIES AND METHODS FOR DRUG DISCOVERY | SGX Pharmaceuticals, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004092727-A2 | COMPOUND LIBRARIES AND METHODS FOR DRUG DISCOVERY | STRUCTURAL GENOMIX, INC. (US) | 2004-10-28 | — | — | WO | disclosed |