Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | KDM4A | O75164 | 3/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.39 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.38 |
| ▸ | TET3 | O43151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857476 | 0.80 | KDM4E (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18741706 | 0.80 | KDM4E (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1002512 | 0.80 | KDM4E (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5355271 | 0.78 | NAPRT (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10766873 | 0.78 | CYP3A4 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10765922 | 0.78 | KDM4E (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1137039 | 0.78 | KDM4E (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10762405 | 0.78 | DPP4 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3112069 | 0.78 | KDM4E (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30639525 | 0.78 | CA12 (0.46) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206481-A | Right-embedded alcohol or fenchyl alcohol ester derivatives of 2-hydroxy nicotinic acid and pharmaceutical application thereof | 苏州南医大创新中心 | 2024-06-18 | — | — | CN | disclosed |
| US-20030018012-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-23 | — | — | US | disclosed |
| EP-1196388-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | Dow AgroSciences LLC (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001005769-A2 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2001-01-25 | — | — | WO | disclosed |
| US-4346076-A | Bis-tetrazoylmethyl substituted cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| EP-0048165-A1 | Bis-tetrazolemethyl substituted beta-lactam antibiotics, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0048169-A2 | Bis-tetrazoylmethyl substituted cephalosporin antibiotics, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4304774-A | Bis-tetrazolmethyl substituted β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018012-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | CYP4X1, CYP1A1, NAT1 | CA12 2199/4885CA1 653/4885CA2 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.