Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368582 | 0.81 | PDE3B (0.55) | PDE3BPDE3APIK3CAPIK3CDPIK3CB | |
| SCHEMBL11362214 | 0.80 | PDE3B (0.39) | PDE3BPDE3AGSK3BAAK1PIK3CA | |
| SCHEMBL11363187 | 0.75 | PDE3B (0.42) | PDE3BPDE3AGSK3BPIK3CAPIK3CD | |
| SCHEMBL11366056 | 0.74 | PDE3B (0.41) | PDE3BPDE3AGSK3BMAPK1MAPK14 | |
| SCHEMBL11240265 | 0.73 | PDE3B (0.68) | PDE3BPDE3AGSK3B | |
| SCHEMBL11375219 | 0.73 | PDE3B (0.41) | PDE3BPDE3AGSK3BMAPK1MAPK14 | |
| SCHEMBL4059109 | 0.72 | PIK3R1 (0.55) | GSK3BPIK3CACDK5CDK5R1 | |
| SCHEMBL11238662 | 0.70 | PDPK1 (0.42) | PDE3BPDE3AGSK3BMAPK14CLK4 | |
| SCHEMBL11379146 | 0.70 | ADORA2A (0.42) | PDE3BPDE3AGSK3B | |
| SCHEMBL3786729 | 0.70 | ADORA2A (0.46) | PDE3BPDE3APIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276293-A | Compositions and their preparation | STERLING DRUG INC. (US) | 1981-06-30 | — | — | US | disclosed |