Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441974 | 0.97 | TDP1 (0.48) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL11377272 | 0.97 | TDP1 (0.48) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL11456350 | 0.91 | TDP1 (0.50) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL29139759 | 0.91 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL11374410 | 0.88 | NPSR1 (0.47) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL11374917 | 0.87 | ALDH1A1 (0.68) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL11374518 | 0.87 | TDP1 (0.45) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL11375868 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL11448925 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 | |
| SCHEMBL11365552 | 0.86 | ATM (0.42) | ALDH1A1TDP1CYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255577-A | Process and intermediates for preparing 3-[4-(disubstituted-amino)phenyl] or | STERLING DRUG INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4200313-A | Carbonless duplicating systems | STERLING DRUG INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4187223-A | 3-[4-(Disubstituted-amino)phenyl]-3-(diphenylamino)phthalides | STERLING DRUG INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4168378-A | THERMOGRAPHY, LEUCO DYES | STERLING DRUG INC. (US) | 1979-09-18 | — | — | US | disclosed |