Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448925 | 1.00 | ALDH1A1 (0.63) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL11374917 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL11441974 | 0.89 | TDP1 (0.48) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL11377272 | 0.89 | TDP1 (0.48) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL11380017 | 0.89 | CYP3A4 (0.51) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL9617636 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL11370697 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL11422435 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL11456350 | 0.84 | TDP1 (0.50) | ALDH1A1HPGDTDP1CYP3A4HIF1A | |
| SCHEMBL11374410 | 0.83 | NPSR1 (0.47) | ALDH1A1HPGDTDP1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255577-A | Process and intermediates for preparing 3-[4-(disubstituted-amino)phenyl] or | STERLING DRUG INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4200313-A | Carbonless duplicating systems | STERLING DRUG INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4187223-A | 3-[4-(Disubstituted-amino)phenyl]-3-(diphenylamino)phthalides | STERLING DRUG INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4168378-A | THERMOGRAPHY, LEUCO DYES | STERLING DRUG INC. (US) | 1979-09-18 | — | — | US | disclosed |