Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563305 | 0.65 | S1PR3 (0.49) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL11563317 | 0.65 | S1PR3 (0.49) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL11561631 | 0.65 | S1PR3 (0.49) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL11558047 | 0.65 | S1PR3 (0.49) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL11557503 | 0.65 | S1PR3 (0.49) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL2583169 | 0.60 | NAAA (0.59) | MEN1KMT2AFAAHMGAMGAA | |
| Heptane SCHEMBL695723 | 0.59 | GAA (0.58) | ALDH1A1MEN1KMT2AFAAHMGAM | |
| SCHEMBL1392816 | 0.58 | LTA4H (0.51) | ALDH1A1KMT2AFAAHMGAMGAA | |
| SCHEMBL6037465 | 0.58 | LTA4H (0.51) | ALDH1A1KMT2AFAAHMGAMGAA | |
| SCHEMBL8865384 | 0.58 | LTA4H (0.51) | ALDH1A1KMT2AFAAHMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243609-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-06 | — | — | US | disclosed |