Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 8/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MYLK | Q15746 | 1/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366071 | 0.88 | P2RX1 (0.42) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL11370625 | 0.83 | HSP90AA1 (0.50) | P2RX1TMPRSS4CYP19A1MEN1KMT2A | |
| SCHEMBL17894223 | 0.80 | MEN1 (0.62) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19640219 | 0.80 | MEN1 (0.62) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17894224 | 0.80 | MEN1 (0.62) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11380402 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL1116804 | 0.73 | HSD17B10 (0.50) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL19130784 | 0.72 | TSHR (0.50) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL19124474 | 0.72 | TSHR (0.50) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL818330 | 0.71 | HSD17B10 (0.48) | MEN1KMT2AMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | disclosed |