Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370625 | 0.89 | HSP90AA1 (0.50) | MEN1KMT2ACNR2HSD17B10TSHR | |
| SCHEMBL11366071 | 0.84 | P2RX1 (0.42) | MEN1KMT2ACNR2HSD17B10TSHR | |
| SCHEMBL818330 | 0.80 | HSD17B10 (0.48) | MEN1KMT2AHSD17B10TSHRMAPK1 | |
| SCHEMBL11370942 | 0.79 | P2RX1 (0.47) | MEN1KMT2ACNR2SMN1; SMN2HTT | |
| SCHEMBL11317922 | 0.78 | HSD17B10 (0.50) | MEN1KMT2AHSD17B10TSHRMAPK1 | |
| SCHEMBL768507 | 0.78 | ALDH1A1 (0.61) | MEN1KMT2AHSD17B10TSHRMAPK1 | |
| SCHEMBL26402 | 0.77 | MEN1 (1.00) | MEN1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL11362042 | 0.77 | ESRRA (0.45) | MEN1KMT2ACNR2TSHRSMN1; SMN2 | |
| SCHEMBL11379540 | 0.76 | MEN1 (0.48) | MEN1KMT2ACNR2HSD17B10TSHR | |
| SCHEMBL11377663 | 0.76 | CNR1 (0.42) | MEN1KMT2ACNR2HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294845-A | ANTILIPEMIC AGENTS | ROUSSEL UCLAF, A CORP. OF FRANCE (FR) | 1981-10-13 | — | — | US | disclosed |