Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11370625 | 0.88 | HSP90AA1 (0.50) | P2RX1MEN1KMT2ACYP19A1HSP90AA1 | |
| SCHEMBL11370942 | 0.88 | P2RX1 (0.47) | P2RX1MEN1KMT2ACYP19A1CNR1 | |
| SCHEMBL11380402 | 0.84 | MEN1 (0.61) | MEN1KMT2AHSP90AA1HSP90AB1ALOX5 | |
| SCHEMBL818330 | 0.76 | HSD17B10 (0.48) | MEN1KMT2AHSP90AA1HSP90AB1ALOX5 | |
| SCHEMBL11035091 | 0.76 | ESR1 (0.51) | P2RX1MEN1KMT2ACYP19A1ESR2 | |
| SCHEMBL11379540 | 0.76 | MEN1 (0.48) | P2RX1MEN1KMT2ACYP19A1HSP90AA1 | |
| SCHEMBL11377663 | 0.75 | CNR1 (0.42) | P2RX1MEN1KMT2ACYP19A1HSP90AA1 | |
| SCHEMBL11317922 | 0.74 | HSD17B10 (0.50) | MEN1KMT2AHSP90AA1ALOX5TSHR | |
| SCHEMBL1155523 | 0.74 | CYP19A1 (0.50) | MEN1KMT2ACYP19A1PGRTSHR | |
| SCHEMBL768507 | 0.74 | ALDH1A1 (0.61) | MEN1KMT2AHSP90AA1HSP90AB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294845-A | ANTILIPEMIC AGENTS | ROUSSEL UCLAF, A CORP. OF FRANCE (FR) | 1981-10-13 | — | — | US | disclosed |