Menthofuran

Menthofuran

SCHEMBL113711

Cc1coc2c1CC[C@@H](C)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
TSHR P16473 3/20 1.00
CYP2A6 P11509 2/20 1.00
CYP2A13 Q16696 1/20 1.00
ALOX5 P09917 1/20 0.38
DRD2 P14416 1/20 0.38
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
GAA P10253 2/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
NOD2 Q9HC29 1/20 0.31
ALOX12 P18054 1/20 0.31
LIMK1 P53667 1/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Menthofuran SCHEMBL12013745 1.00 ALDH1A1 (1.00) ALDH1A1TSHRCYP2A6CYP2A13ALOX5
Menthofuran SCHEMBL1472618 1.00 ALDH1A1 (1.00) ALDH1A1TSHRCYP2A6CYP2A13ALOX5
SCHEMBL28736052 0.86 ALDH1A1 (0.76) ALDH1A1TSHRCYP2A6CYP2A13ALOX5
Menthofuran SCHEMBL23326200 0.82 CYP2A6 (0.67) ALDH1A1TSHRCYP2A6CYP2A13ALOX5
SCHEMBL13021597 0.70
SCHEMBL13021602 0.70 ALDH1A1 (0.53) ALDH1A1TSHRCYP2A6CYP2A13ALOX5
SCHEMBL10013879 0.64 ALDH1A1 (0.47) ALDH1A1TSHRCYP2A6CYP2A13KDM4E
SCHEMBL351647 0.64 ALDH1A1 (0.47) ALDH1A1TSHRCYP2A6CYP2A13KDM4E
SCHEMBL13931594 0.64 ALDH1A1 (0.47) ALDH1A1TSHRCYP2A6CYP2A13KDM4E
SCHEMBL12267962 0.64 ALDH1A1 (0.47) ALDH1A1TSHRCYP2A6CYP2A13KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2384 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122084781-A Method for detecting oxidative condensed tannin in red wine 2026-05-26 CN claimed
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
US-12514798-B2 Use of [6]-paradol for stabilization of cosmetic compositions SYMRISE AG (DE) 2026-01-06 US claimed
US-12446586-B2 Oil-based insecticidal and insect repellent compositions S. C. JOHNSON & SON, INC. (US) 2025-10-21 US claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
EP-4565194-A1 ODOR AND COLORANT STABILIZED COMPOSITIONS Symrise AG (DE) 2025-06-11 EP claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US claimed
CN-119930592-A Menthofuran derivative of epigallocatechin gallate, and preparation method and application thereof 华中农业大学 2025-05-06 CN claimed
CN-119924491-A Flavoring composition with balanced taste characteristics 西姆莱斯有限公司 2025-05-06 CN claimed
CN-119744164-A Odor and colorant stable compositions 西姆莱斯股份公司 2025-04-01 CN claimed
US-5047251-A Stable peppermint oil having reduced pulegone content and method of producing the same A. M. TODD COMPANY (US) 1991-09-10 US claimed
US-4861616-A Stable peppermint oil having reduced pulegone content and method of producing the same A. M. TODD COMPANY (US) 1989-08-29 US claimed
EP-0113988-B1 A PROCESS FOR PREPARING A REDUCED-MENTHOFURAN-CONTENT PEPPERMINT OIL WARNER-LAMBERT COMPANY (US) 1988-06-22 EP claimed
US-4478864-A Confections containing stabilized peppermint oil WARNER-LAMBERT COMPANY (US) 1984-10-23 US claimed
US-4476142-A METHOFURAN ADDUCT, OXIDATION RESISTANCE WARNER-LAMBERT COMPANY (US) 1984-10-09 US claimed
EP-0113989-A2 Reduced-menthofuran-content peppermint oil flavoured compositions WARNER-LAMBERT COMPANY (US) 1984-07-25 EP claimed
EP-0113988-A2 A process for preparing a reduced-menthofuran-content peppermint oil WARNER-LAMBERT COMPANY (US) 1984-07-25 EP claimed
US-4456621-A Process for flavoring chewing gum with stabilized peppermint oil WARNER-LAMBERT COMPANY (US) 1984-06-26 US claimed
US-4440790-A Process for stabilizing peppermint oil WARNER-LAMBERT COMPANY (US) 1984-04-03 US claimed
US-4240969-A Synthesis of menthofuran SCM CORPORATION (US) 1980-12-23 US claimed