SCHEMBL351647

SCHEMBL351647

Cc1coc2c1C(=O)C[C@@H](C)C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
CYP2A6 P11509 2/20 0.47
TSHR P16473 2/20 0.47
CYP2A13 Q16696 1/20 0.47
NQO1 P15559 2/20 0.34
POR P16435 2/20 0.34
MAPK1 P28482 2/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
KDM4E B2RXH2 1/20 0.33
STAT3 P40763 1/20 0.32
MAOA P21397 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013879 1.00 ALDH1A1 (0.47) ALDH1A1CYP2A6TSHRCYP2A13NQO1
SCHEMBL12978354 0.81 CYP2A6 (0.42) ALDH1A1CYP2A6TSHRCYP2A13
SCHEMBL6947652 0.76 HTR2A (0.34) ALDH1A1CYP2A6TSHRCYP2A13GABRA1
SCHEMBL7683472 0.74 MAP1LC3B (0.47) ALDH1A1TSHRMAPK1HPGD
SCHEMBL6804346 0.73 MAOA (0.48) KDM4EMAOAMAPT
SCHEMBL7681124 0.73 MAP1LC3B (0.42) ALDH1A1KDM4EKMT2AMAPTHPGD
SCHEMBL7689340 0.72 LMNA (0.43) ALDH1A1TSHRMAPK1KMT2AHPGD
SCHEMBL7687762 0.72 POLB (0.50) ALDH1A1TSHRMAPK1KDM4EKMT2A
SCHEMBL7678724 0.71 LMNA (0.34) ALDH1A1NQO1PORMAPK1KDM4E
SCHEMBL7689174 0.71 LDHA (0.40) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3927309-B1 USE OF EVODONE OR A DERIVATIVE THEREOF AS A COOLING AGENT ROBERTET SA (FR) 2025-03-12 EP claimed
US-12133909-B2 Use of evodone or a derivative thereof as a cooling agent ROBERTET S.A. (FR) 2024-11-05 US claimed
US-20220040077-A1 USE OF EVODONE OR A DERIVATIVE THEREOF AS A COOLING AGENT ROBERTET S.A. (FR) 2022-02-10 US claimed
EP-3927309-A1 USE OF EVODONE OR A DERIVATIVE THEREOF AS A COOLING AGENT Robertet S.A. (FR) 2021-12-29 EP claimed
EP-2405760-B1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS, AND USE THEREOF CHARABOT (FR) 2019-06-19 EP claimed
US-10258036-B2 Extract of Euodia suaveolens Scheff, repellent compositions and use thereof CHARABOT (FR) 2019-04-16 US claimed
US-20160198706-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS AND USE THEREOF CHARABOT (FR) 2016-07-14 US claimed
WO-2016097496-A1 USE OF EVODONE DERIVATIVES AS REPELLENT, NOVEL EVODONE DERIVATIVES AND SYNTHESIS PROCESS CHARABOT (FR) 2016-06-23 WO claimed
US-9345659-B2 Use of melicope extracts to improve conditions caused by excess lipids AVON PRODUCTS, INC. (US) 2016-05-24 US claimed
US-9320273-B2 Extract of euodia suaveolens scheff, repellent compositions and use thereof CHARABOT (FR) 2016-04-26 US claimed
US-20140271953-A1 Use of Melicope Extracts to Improve Conditions Caused by Excess Lipids AVON PRODUCTS, INC. (US) 2014-09-18 US claimed
WO-2014092684-A2 USE OF MELICOPE EXTRACTS TO IMPROVE CONDITIONS CAUSED BY EXCESS LIPIDS AVON PRODUCTS, INC. (US) 2014-06-19 WO claimed
US-20130274326-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS AND USE THEREOF CHARABOT (FR) 2013-10-17 US claimed
US-8481088-B2 Extract of Euodia suaveolens Scheff, repellent compositions and use thereof CHARABOT (FR) 2013-07-09 US claimed
US-20120015054-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS AND USE THEREOF CHARABOT (FR) 2012-01-19 US claimed
EP-3927309-B1 USE OF EVODONE OR A DERIVATIVE THEREOF AS A COOLING AGENT ROBERTET SA (FR) 2025-03-12 EP disclosed
US-12133909-B2 Use of evodone or a derivative thereof as a cooling agent ROBERTET S.A. (FR) 2024-11-05 US disclosed
EP-2405760-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS, AND USE THEREOF Charabot (FR) 2012-01-18 EP disclosed
WO-2010103207-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS, AND USE THEREOF CHARABOT (FR) 2010-09-16 WO disclosed
WO-2010103207-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS, AND USE THEREOF CHARABOT (FR) 2010-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160198706-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS AND USE THEREOF ITCH, ELANE, CCL11 ALDH1A1 276/4885CYP2A6 1257/4885TSHR 4504/4885
US-20120015054-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS AND USE THEREOF ITCH, ELANE, CCL11 ALDH1A1 276/4885CYP2A6 1257/4885TSHR 4504/4885
US-12133909-B2 Use of evodone or a derivative thereof as a cooling agent OPRK1, CYP3A43, OPRM1 ALDH1A1 133/4885CYP2A6 152/4885TSHR 3066/4885
US-10258036-B2 Extract of Euodia suaveolens Scheff, repellent compositions and use thereof ITCH, ELANE, CCL11 ALDH1A1 276/4885CYP2A6 1257/4885TSHR 4504/4885
US-20130274326-A1 EXTRACT OF EUODIA SUAVEOLENS SCHEFF, REPELLENT COMPOSITIONS AND USE THEREOF ITCH, ELANE, CCL11 ALDH1A1 276/4885CYP2A6 1257/4885TSHR 4504/4885
US-20220040077-A1 USE OF EVODONE OR A DERIVATIVE THEREOF AS A COOLING AGENT OPRK1, CYP3A43, OPRM1 ALDH1A1 133/4885CYP2A6 152/4885TSHR 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.