Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380622 | 0.86 | ALDH1A1 (0.50) | RXFP1HTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11639817 | 0.83 | RXFP1 (0.45) | RXFP1TSHRHTTLMNAMEN1 | |
| SCHEMBL11372327 | 0.81 | ALDH1A1 (0.53) | RXFP1TSHRHTTLMNAMEN1 | |
| SCHEMBL11372417 | 0.80 | RXFP1 (0.45) | RXFP1TSHRHTTLMNAMEN1 | |
| SCHEMBL11372364 | 0.80 | RXFP1 (0.62) | RXFP1TSHRHTTLMNAMEN1 | |
| SCHEMBL11381859 | 0.79 | HIF1A (0.46) | RXFP1TSHRHTTLMNAMEN1 | |
| SCHEMBL11369368 | 0.78 | RXFP1 (0.50) | RXFP1TSHRHTTLMNAMEN1 | |
| SCHEMBL11373100 | 0.77 | MEN1 (0.50) | TSHRMEN1KMT2AFEN1ATM | |
| SCHEMBL11365331 | 0.72 | RXFP1 (0.54) | RXFP1TSHRHTTLMNAMEN1 | |
| SCHEMBL11365043 | 0.71 | RXFP1 (0.53) | RXFP1TSHRHTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281131-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1981-07-28 | — | — | US | disclosed |
| US-4187309-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-05 | — | — | US | disclosed |