Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639817 | 0.88 | RXFP1 (0.45) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL11372185 | 0.86 | RXFP1 (0.42) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL11377362 | 0.84 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL11377101 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL11393959 | 0.81 | LMNA (0.67) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL11388773 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL11375460 | 0.80 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL5331127 | 0.80 | KDM4E (0.58) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL11383233 | 0.80 | LMNA (0.53) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL11385764 | 0.75 | LMNA (0.65) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273930-A | INTERMEDIATES FOR THE 4-ALKOXY ANTIALLERGENS | SANDOZ, INC. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4190659-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-26 | — | — | US | disclosed |