SCHEMBL113722

SCHEMBL113722

CC(C)(C)c1ccc(CO)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 5/20 0.61
LMNA P02545 1/20 0.52
TYR P14679 1/20 0.52
TSHR P16473 3/20 0.48
RECQL P46063 1/20 0.46
KCNH2 Q12809 1/20 0.45
TP53 P04637 1/20 0.45
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
IKBKB O14920 1/20 0.44
NR1H4 Q96RI1 3/20 0.43
HDAC3 O15379 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
APP P05067 1/20 0.42
MAP3K5 Q99683 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821120 0.93 EPHX2 (0.56) EPHX2LMNATYRTSHRRECQL
SCHEMBL26057873 0.87 LTA4H (0.59) EPHX2LMNATYRRECQLPPARG
SCHEMBL11772398 0.87 RARB (0.55) EPHX2LMNATYRTSHRRECQL
SCHEMBL13863328 0.87 CYP1A2 (0.53) EPHX2LMNATYRTSHRTP53
Toluene SCHEMBL5955731 0.85 TSHR (0.52) EPHX2LMNATYRTSHRBCHE
SCHEMBL787308 0.84 ESR1 (0.52) EPHX2TSHRPPARGPPARA
SCHEMBL10392943 0.84 SRD5A2 (0.67) EPHX2LMNANR1H4
SCHEMBL6745030 0.83 TSHR (0.48) EPHX2TYRTSHRPPARGPPARA
SCHEMBL12017412 0.82 RAB9A (0.69) EPHX2LMNARECQLKCNH2NR1H4
SCHEMBL5510152 0.82 APP (0.70) EPHX2LMNANR1H4APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1538 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954644-A Method for producing succinic acid ester by maleic anhydride 上海师范大学 2025-05-09 CN claimed
US-20250136891-A1 PERFUME CONCRETE AND ABSOLUTE WHICH ARE OBTAINED BY ORGANIC (POLY)OL SOLVENT EXTRACTION FROM SOLID NATURAL SUBSTANCES L'OREAL (FR) 2025-05-01 US claimed
EP-4511463-A2 PERFUME CONCRETE AND ABSOLUTE WHICH ARE OBTAINED BY ORGANIC (POLY)OL SOLVENT EXTRACTION FROM SOLID NATURAL SUBSTANCES L'OREAL (FR) 2025-02-26 EP claimed
EP-3778722-B1 POLYCARBONATE RESIN COMPOSITION PELLET, PELLET PRODUCTION METHOD AND MOLDED ACTICLE THEREOF MITSUBISHI ENG PLASTICS CORP (JP) 2024-12-11 EP claimed
CN-116332710-B Preparation method of metal-catalyzed benzyl ether and prepared benzyl ether 合肥工业大学 2024-11-26 CN claimed
CN-115369432-B Method for preparing nitrile by electrocatalytic coupling of primary alcohol and ammonia substance 大连理工大学 2024-08-20 CN claimed
CN-118085486-A Type II porous liquid containing high-concentration coordination cage and preparation method and application thereof 南京工业大学 2024-05-28 CN claimed
CN-113493388-B Synthesis method of butenafine hydrochloride 鲁南制药集团股份有限公司 2024-05-10 CN claimed
WO-2023203098-A2 PERFUME CONCRETE AND ABSOLUTE WHICH ARE OBTAINED BY ORGANIC (POLY)OL SOLVENT EXTRACTION FROM SOLID NATURAL SUBSTANCES L'OREAL (FR) 2023-10-26 WO claimed
CN-114634451-B Method for synthesizing pyrimidine derivative mediated by t-BuOK 南京师范大学 2023-10-24 CN claimed
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
EP-1115693-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
EP-0381656-A1 Alcohol-soluble/water-insoluble oil-containing antifreeze FIRST BRANDS CORPORATION (US) 1990-08-08 EP claimed
US-4931455-A Alkylaminopyrimidine derivative and insecticide, acaricide and fungicide containing the same as active ingredient UBE INDUSTRIES, LTD. (JP) 1990-06-05 US claimed
US-4613622-A Sebosuppressive preparations containing benzyl alcohol derivatives HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-09-23 US claimed
EP-0012942-B1 ELECTROLYTIC PROCESS FOR PRODUCING BENZALDEHYDES BASF Aktiengesellschaft (DE) 1982-01-27 EP claimed
EP-0012942-A2 Electrolytic process for producing benzaldehydes BASF Aktiengesellschaft (DE) 1980-07-09 EP claimed
US-4148696-A Electrochemical oxidation of activated alkyl aromatic compounds UOP INC. (US) 1979-04-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity CETP, LCAT, MTTP EPHX2 2024/4885LMNA 1157/4885TYR 3311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.