Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374027 | 1.00 | FPR2 (0.47) | FPR2ALDH1A1ALOX15GAAKMT2A | |
| SCHEMBL11374378 | 0.83 | ATM (0.44) | ALDH1A1 | |
| SCHEMBL11374361 | 0.83 | ATM (0.44) | ALDH1A1 | |
| SCHEMBL11371629 | 0.79 | KDM4E (0.39) | ALDH1A1GAAKMT2APKM | |
| SCHEMBL11371612 | 0.79 | KDM4E (0.39) | ALDH1A1GAAKMT2APKM | |
| SCHEMBL11374993 | 0.77 | MAPK1 (0.40) | ALDH1A1GAAKMT2ANPSR1 | |
| SCHEMBL11375003 | 0.77 | MAPK1 (0.40) | ALDH1A1GAAKMT2ANPSR1 | |
| SCHEMBL11376027 | 0.73 | KDM4E (0.43) | ALDH1A1GAAKMT2APKMPOLB | |
| SCHEMBL28650934 | 0.70 | KMT2A (0.53) | FPR2ALDH1A1ALOX15GAAKMT2A | |
| SCHEMBL9223334 | 0.69 | NPSR1 (0.55) | ALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267344-A | 3-PENTA/ALKOXY/BENZYL-; -XANTHYL-, -THIOXANTHYL-, OR -SELENOXANTHYLOXAZOLIDINE-2,5-DIONES | PROTEINKEMISK INSTITUT. TILKNYTTET AKADEMIET FOR DE TEKNISKE VIDENSKABER (DK) | 1981-05-12 | — | — | US | disclosed |