Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374993 | 1.00 | MAPK1 (0.40) | MAPK1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL11371629 | 0.86 | KDM4E (0.39) | MAPK1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL11371612 | 0.86 | KDM4E (0.39) | MAPK1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL11374361 | 0.81 | ATM (0.44) | ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11374378 | 0.81 | ATM (0.44) | ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11374041 | 0.77 | FPR2 (0.47) | ALDH1A1KMT2ANPSR1GAA | |
| SCHEMBL11374027 | 0.77 | FPR2 (0.47) | ALDH1A1KMT2ANPSR1GAA | |
| SCHEMBL11376027 | 0.75 | KDM4E (0.43) | ALDH1A1MAPTHPGDKDM4ETDP1 | |
| SCHEMBL9862211 | 0.66 | KMT2A (0.66) | MAPK1MAPTKDM4EHSD17B10TDP1 | |
| SCHEMBL10802344 | 0.65 | MAPT (0.40) | ALDH1A1MAPTKDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267344-A | 3-PENTA/ALKOXY/BENZYL-; -XANTHYL-, -THIOXANTHYL-, OR -SELENOXANTHYLOXAZOLIDINE-2,5-DIONES | PROTEINKEMISK INSTITUT. TILKNYTTET AKADEMIET FOR DE TEKNISKE VIDENSKABER (DK) | 1981-05-12 | — | — | US | disclosed |