Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27751166 | 0.78 | LMNA (0.69) | LMNATP53ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4636133 | 0.77 | MAPT (0.70) | LMNATP53ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11009364 | 0.77 | SMN1; SMN2 (0.69) | LMNATP53ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11363579 | 0.77 | ALDH1A1 (1.00) | LMNATP53ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL3547359 | 0.77 | MAPT (0.80) | LMNAALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL676083 | 0.76 | SMN1; SMN2 (0.64) | LMNATP53ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL15581471 | 0.76 | LMNA (0.54) | LMNATP53ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL2753912 | 0.76 | LMNA (0.69) | LMNATP53ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11376337 | 0.76 | SMN1; SMN2 (0.67) | LMNATP53ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1340139 | 0.75 | SMN1; SMN2 (0.70) | LMNATP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254259-A | HERBICIDES | INDIANA UNIVERSITY FOUNDATION (US) | 1981-03-03 | — | — | US | disclosed |