Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077027 | 0.79 | POLB (0.66) | NPSR1L3MBTL1POLBHTTMAPT | |
| SCHEMBL11086924 | 0.76 | L3MBTL1 (0.50) | NPSR1L3MBTL1POLBHTTMAPT | |
| SCHEMBL11069378 | 0.76 | HTT (0.52) | NPSR1L3MBTL1POLBHTTPARP10 | |
| SCHEMBL20592356 | 0.75 | KMT2A (0.53) | NPSR1L3MBTL1POLBHTTMAPT | |
| SCHEMBL26490327 | 0.74 | KMT2A (0.56) | NPSR1L3MBTL1POLBHTTMAPT | |
| SCHEMBL725404 | 0.74 | KMT2A (0.76) | NPSR1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11072867 | 0.73 | TNF (0.47) | NPSR1L3MBTL1POLBHTTMAPT | |
| Bromide SCHEMBL29588519 | 0.72 | KMT2A (0.73) | NPSR1POLBMAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16050041 | 0.72 | KMT2A (0.73) | NPSR1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8083703 | 0.72 | KMT2A (0.53) | NPSR1POLBMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261995-A | DISORDERS OF CENTRAL NERVOUS SYSTEM AND CARDIOVASCULAR SYSTEM; HYPOTENSIVE | SYNTEX (U.S.A.) INC. (US) | 1981-04-14 | — | — | US | disclosed |