Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | CA6 | P23280 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271087 | 0.84 | ALDH1A1 (0.41) | CYP3A4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL27514498 | 0.77 | GLO1 (0.42) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL11374762 | 0.76 | ALDH1A1 (0.36) | CYP3A4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL537616 | 0.75 | CYP3A4 (0.47) | CYP3A4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL3030086 | 0.75 | CYP3A4 (0.47) | CYP3A4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL29927238 | 0.75 | CYP3A4 (0.47) | CYP3A4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL2825688 | 0.74 | KDM4E (0.55) | CYP3A4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL31494237 | 0.74 | KDM4E (0.55) | CYP3A4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL985182 | 0.74 | KDM4E (0.41) | CYP3A4ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL270432 | 0.74 | ALDH1A1 (0.41) | CYP3A4ACHEKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302241-A | N-(PYRIMIDIN-2-YL-AMINOCARBONYL) ARYL SULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-24 | — | — | US | disclosed |