Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL11375143 | 0.79 | ESR1 (0.44) | SLC6A4PKMGAALMNAALDH1A1 | |
| Fumaric Acid SCHEMBL11375137 | 0.79 | ESR1 (0.44) | SLC6A4PKMGAALMNAALDH1A1 | |
| SCHEMBL11097016 | 0.69 | ACACB (0.48) | ACACB | |
| SCHEMBL9319775 | 0.66 | PDE10A (0.39) | LMNAHPGDALDH1A1KMT2AGLA | |
| SCHEMBL3694965 | 0.66 | OPRM1 (0.54) | SLC6A4ACACB | |
| SCHEMBL17865626 | 0.65 | SLC6A4 (0.77) | SLC6A4CYP2D6 | |
| SCHEMBL9518131 | 0.62 | AOC3 (0.39) | HTTLMNAALDH1A1ACACBKMT2A | |
| SCHEMBL9516954 | 0.62 | ACACB (0.36) | HTTLMNAHPGDALDH1A1KDM4E | |
| SCHEMBL16180336 | 0.61 | SLC6A4 (0.66) | SLC6A4KMT2ACYP2D6 | |
| SCHEMBL16180337 | 0.61 | SLC6A4 (0.66) | SLC6A4KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260619-A | ANTIISCHEMIC | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |