Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11373368 | 0.82 | MAPT (0.54) | ALDH1A1SMN1; SMN2CYP3A4MAPTPOLB | |
| SCHEMBL16115920 | 0.81 | L3MBTL1 (0.55) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL7279240 | 0.81 | F3 (0.49) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL11371533 | 0.81 | TDP1 (0.48) | ALDH1A1CYP2A6THRBATMSMN1; SMN2 | |
| SCHEMBL10999566 | 0.81 | THRB (0.66) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL2478128 | 0.81 | PARP10 (0.57) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL5749467 | 0.81 | CA1 (0.66) | F3ALDH1A1CYP1A2MAPTKMT2A | |
| SCHEMBL30105639 | 0.80 | GSK3B (0.73) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL2477032 | 0.80 | HDAC8 (0.56) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL1237222 | 0.80 | GSK3B (0.73) | GSK3BF3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288364-A | REACTING A 3-/2-HYDROXYIMINOACETYLAMINO/-2-OXOAZETIDINE WITH AN ORGANIC CARBONATE OR ACYL HALIDE | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0005507-A1 | Process for the fragmentation of 3-(2-hydroxyimino-acetylamino)-2-oxo azetidin compounds and compounds obtained thereby | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |