Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381564 | 0.99 | HRH3 (0.54) | HRH3KCNH2ADRA2CSLC6A3PDE4A | |
| SCHEMBL10995561 | 0.78 | HRH3 (0.53) | HRH3KCNH2ADRA2CSLC6A3GPR119 | |
| SCHEMBL11374409 | 0.78 | GPR119 (0.63) | HRH3KCNH2ADRA2CSLC6A3GPR119 | |
| SCHEMBL11366599 | 0.78 | GPR119 (0.63) | HRH3KCNH2ADRA2CSLC6A3PDE4A | |
| SCHEMBL11365384 | 0.78 | HRH3 (0.51) | HRH3KCNH2ADRA2CSLC6A3GPR119 | |
| SCHEMBL11368296 | 0.78 | GPR119 (0.61) | HRH3KCNH2ADRA2CSLC6A3GPR119 | |
| SCHEMBL11369319 | 0.78 | HRH3 (0.51) | HRH3KCNH2ADRA2CSLC6A3GPR119 | |
| SCHEMBL11369154 | 0.78 | GPR119 (0.60) | HRH3KCNH2ADRA2CSLC6A3GPR119 | |
| Hydrochloric Acid SCHEMBL11367458 | 0.77 | HRH3 (0.52) | HRH3KCNH2ADRA2CSLC6A3GPR119 | |
| SCHEMBL11371714 | 0.75 | PTPN1 (0.56) | HRH3KCNH2ADRA2CSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271163-A | HYPOTENSIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | disclosed |