Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 3/20 | 0.49 |
| ▸ | CPT2 | P23786 | 1/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379685 | 0.86 | PREP (0.60) | MEN1KMT2ADPP4PREPADRB2 | |
| SCHEMBL11376413 | 0.85 | PREP (0.59) | MEN1KMT2ADPP4PREPGAA | |
| SCHEMBL11371767 | 0.82 | DPP4 (0.45) | CPT1AMEN1KMT2ADPP4PREP | |
| SCHEMBL11201904 | 0.79 | DPP4 (0.49) | MEN1KMT2ADPP4GAAADRB2 | |
| SCHEMBL11376415 | 0.79 | PREP (0.75) | DPP4PREPMAPTSMN1; SMN2KDM4E | |
| SCHEMBL11380215 | 0.77 | DPP4 (0.50) | DPP4PREPL3MBTL1ALDH1A1POLB | |
| SCHEMBL4729725 | 0.77 | SMN1; SMN2 (0.50) | MEN1KMT2ADPP4GAANPC1 | |
| SCHEMBL11376269 | 0.77 | PREP (0.53) | DPP4PREPADRB2ADRB1 | |
| SCHEMBL11383827 | 0.73 | FKBP1A (0.51) | MEN1KMT2ADPP4NPC1MAPT | |
| SCHEMBL11386961 | 0.73 | DPP4 (0.44) | DPP4PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |