Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386013 | 0.82 | PREP (0.76) | PREPDPP7DPP4 | |
| SCHEMBL11379685 | 0.82 | PREP (0.60) | PREPDPP7DPP4ADRB2ADRB1 | |
| SCHEMBL11373108 | 0.80 | NFKB1 (0.44) | PREPDPP4ADRB2ADRB1 | |
| SCHEMBL11380874 | 0.80 | PREP (0.73) | PREPDPP7DPP4 | |
| SCHEMBL11381209 | 0.78 | PREP (0.58) | PREPDPP7DPP4 | |
| SCHEMBL11377789 | 0.78 | DPP4 (0.50) | PREPDPP7DPP4 | |
| SCHEMBL4729725 | 0.78 | SMN1; SMN2 (0.50) | DPP4 | |
| SCHEMBL11375303 | 0.77 | CPT1A (0.54) | PREPDPP4ADRB2ADRB1 | |
| SCHEMBL11375543 | 0.76 | PREP (0.53) | PREPDPP7DPP4 | |
| SCHEMBL11379356 | 0.76 | ABAT (0.54) | PREPDPP7DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |