Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375428 | 1.00 | OPRD1 (0.41) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11375006 | 0.82 | OPRD1 (0.49) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11375005 | 0.82 | OPRD1 (0.49) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11371327 | 0.79 | OPRD1 (0.44) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11368410 | 0.79 | OPRD1 (0.42) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11368406 | 0.79 | OPRD1 (0.42) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11371156 | 0.78 | BACE1 (0.46) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11371141 | 0.78 | BACE1 (0.46) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11371161 | 0.77 | L3MBTL3 (0.41) | OPRD1OPRM1OPRK1OPRL1MAPT | |
| SCHEMBL11371163 | 0.77 | L3MBTL3 (0.41) | OPRD1OPRM1OPRK1OPRL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |