Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346139 | 0.85 | KMT2A (0.68) | POLBCYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL11370320 | 0.83 | KMT2A (0.54) | MAPTPKMATMPOLBCYP1A2 | |
| SCHEMBL11374305 | 0.80 | KMT2A (0.46) | MAPTPOLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11375075 | 0.77 | PTGS2 (0.45) | MAPTPOLBKMT2AALDH1A1HPGD | |
| SCHEMBL11348514 | 0.76 | PTGS2 (0.56) | POLBCYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL11369640 | 0.75 | KMT2A (0.67) | MAPTPKMPOLBKMT2AALDH1A1 | |
| SCHEMBL23022527 | 0.75 | MAPT (0.59) | MAPTPKMATMPOLBCYP1A2 | |
| SCHEMBL11574182 | 0.75 | KMT2A (0.55) | KMT2AALDH1A1MEN1PTGS2 | |
| SCHEMBL18362869 | 0.73 | MAPT (0.57) | MAPTPKMATMPOLBCYP1A2 | |
| SCHEMBL2987502 | 0.73 | MAPT (0.49) | MAPTPKMATMPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272507-A | Phenylaminothiophenacetic acids, their synthesis, compositions and use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-06-09 | — | — | US | disclosed |