Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346139 | 0.88 | KMT2A (0.68) | KMT2APTGS2ALDH1A1LMNAHTT | |
| SCHEMBL11375487 | 0.83 | MAPT (0.52) | KMT2APTGS2ALDH1A1CYP1A2POLB | |
| SCHEMBL11374305 | 0.83 | KMT2A (0.46) | KMT2APTGS2ALDH1A1LMNACXCL8 | |
| SCHEMBL11367869 | 0.80 | PTGS2 (0.51) | KMT2APTGS2LMNAHTTCHRNA7 | |
| SCHEMBL11574182 | 0.77 | KMT2A (0.55) | KMT2APTGS2ALDH1A1LMNAHTT | |
| SCHEMBL11348514 | 0.76 | PTGS2 (0.56) | KMT2APTGS2LMNACXCL8CYP1A2 | |
| SCHEMBL11373966 | 0.74 | KMT2A (0.50) | KMT2APTGS2ALDH1A1LMNACXCL8 | |
| SCHEMBL8956524 | 0.72 | PTGS2 (0.62) | KMT2APTGS2ALDH1A1CHRNA7CXCL8 | |
| SCHEMBL11564156 | 0.71 | PTGS2 (0.61) | KMT2APTGS2LMNACXCL8CYP1A2 | |
| SCHEMBL28785117 | 0.71 | ACLY (0.54) | KMT2APTGS2ALDH1A1LMNACXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272507-A | Phenylaminothiophenacetic acids, their synthesis, compositions and use | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-06-09 | — | — | US | disclosed |