Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 12/20 | 0.41 |
| ▸ | ACHE | P22303 | 9/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375571 | 1.00 | CNR1 (0.45) | CNR1CNR2BACE1ACHEBCHE | |
| SCHEMBL11381203 | 0.92 | CNR1 (0.48) | CNR1CNR2BACE1ACHEBCHE | |
| SCHEMBL11381200 | 0.92 | CNR1 (0.48) | CNR1CNR2BACE1ACHEBCHE | |
| SCHEMBL11380203 | 0.89 | ACHE (0.47) | BACE1ACHEBCHEMAPTL3MBTL3 | |
| SCHEMBL11380207 | 0.89 | ACHE (0.47) | BACE1ACHEBCHEMAPTL3MBTL3 | |
| SCHEMBL11370328 | 0.82 | MAPT (0.59) | CNR1CNR2BACE1ACHEBCHE | |
| SCHEMBL11370326 | 0.82 | MAPT (0.59) | CNR1CNR2BACE1ACHEBCHE | |
| SCHEMBL11373892 | 0.80 | BACE1 (0.56) | BACE1ACHEBCHEMAPTL3MBTL3 | |
| SCHEMBL11373895 | 0.80 | BACE1 (0.56) | BACE1ACHEBCHEMAPTL3MBTL3 | |
| SCHEMBL11373880 | 0.79 | ACHE (0.62) | BACE1ACHEBCHESMN1; SMN2L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267318-A | 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof | G. D. SEARLE & CO. (US) | 1981-05-12 | — | — | US | disclosed |