Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375639 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL6541950 | 0.90 | ALDH1A1 (0.48) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL11386885 | 0.88 | NR1I2 (0.56) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL11376725 | 0.88 | NR1I2 (0.56) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL11376732 | 0.88 | NR1I2 (0.56) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL6542342 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL6243253 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL9482975 | 0.81 | TDP1 (0.49) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL9482968 | 0.81 | TDP1 (0.49) | ALDH1A1MAPTTDP1KDM4EHSD17B10 | |
| SCHEMBL9481092 | 0.81 | TDP1 (0.44) | ALDH1A1MAPTTDP1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254119-A | 3-Unsubstituted-3-cephem compounds | SHIONOGI & CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |