Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760188 | 0.91 | NR1I2 (0.42) | ALDH1A1HSD17B10TDP1MAPTKDM4E | |
| SCHEMBL6760190 | 0.91 | NR1I2 (0.42) | ALDH1A1HSD17B10TDP1MAPTKDM4E | |
| SCHEMBL6541950 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TDP1MAPTKDM4E | |
| SCHEMBL6542342 | 0.89 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1MAPTKDM4E | |
| SCHEMBL7542677 | 0.88 | NR1I2 (0.51) | ALDH1A1HSD17B10TDP1MAPTNR1I2 | |
| SCHEMBL7225660 | 0.88 | KCNH2 (0.43) | ALDH1A1HSD17B10TDP1MAPTKDM4E | |
| SCHEMBL7542672 | 0.88 | NR1I2 (0.51) | ALDH1A1HSD17B10TDP1MAPTNR1I2 | |
| SCHEMBL7225657 | 0.88 | KCNH2 (0.43) | ALDH1A1HSD17B10TDP1MAPTKDM4E | |
| SCHEMBL6542731 | 0.88 | KCNH2 (0.43) | ALDH1A1HSD17B10TDP1MAPTKDM4E | |
| SCHEMBL6542726 | 0.88 | KCNH2 (0.43) | ALDH1A1HSD17B10TDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222194-B1 | 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIC ACID ANTIBIOTICS AND PRODRUGS THEREOF | TRINE PHARMACEUTICALS INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6723716-B1 | BACTERICIDE FOR STAPHYLOCOCCUS | ESSENTIAL THERAPEUTICS, INC. | 2004-04-20 | — | — | US | disclosed |